K9 Advantix II for Dogs 12-Month Supply

Regularly: $174.99
Today's savings: 25%

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In Stock. Usually Ships within 24 hours.



In Stock. Usually Ships within 24 hours.



In Stock. Usually Ships within 24 hours.

Over 55lb


In Stock. Usually Ships within 24 hours.

Shipping weight = 0.40 lb.


Product Summary:

K9 Advantix II Dog: 12-Month Supply

K9 Advantix II delivers pest protection through topical action. It protects against fleas (flea eggs and larvae), ticks, mosquitoes, biting flies, and lice. It combines imidacloprid and permethrin with insect growth regulator pyriproxyfen, which interferes with the hormone signaling of molting insects so that fleas in immature stages are unable to molt. K9 Advantix II is for monthly use on puppies (as young as 7 weeks old) and dogs. Do not use on cats.

  • Repels and kills ticks, fleas, and mosquitoes
  • Repels biting flies
  • Kills lice
  • Kills all life stages of fleas
  • Prevents development of fleas, flea eggs, and larvae
  • Kills fleas within 12 hours of initial application
  • Kills reinfesting fleas within two hours
  • Protects against ticks that may transmit organisms that can cause Lyme disease, Rocky Mountain spotted fever, Ehrlichiosis, Anaplasmosis
  • Waterproof; continues to work after a bath or weekly swimming (for optimal results, use a non-detergent shampoo)
  • One application lasts for a month
  • Can be used on puppies as young as 7 weeks old
  • Easy-to-follow application instructions on the back of every package
Item Specifications:

4-10 lb.: Green
11-20 lb.: Teal
21-55 lb.: Red
Over 55 lb.: Blue

Includes 12 applicators

Apply entire contents of tube evenly to two to three spots on the top of the back from the shoulder to the base of the tail. Monthly application.

Length of Effectiveness:
Under normal conditions, the product is effective for a month. However, in cases of severe flea infestation, retreatment may be necessary earlier than four weeks. Do not retreat more often than once every seven days. After flea control is attained, return to a monthly retreatment schedule.

8.80% Imidacloprid
44.00% Permethrin
0.44% Pyriproxyfen
46.76% other ingredients
Active ingredients work synergistically. The combination of imidacloprid with permethrin exerts a unique synergistic effect on the arthropod nervous system that is greater than either ingredient alone. Each compound acts on a different receptor area of the nerve cell.
Imidacloprid (nicotinic receptors) irreversibly opens nicotinic receptors on postsynaptic neurons, resulting in constant neuromuscular stimulation, spastic paralysis, and death.
Permethrin (sodium channels) causes prolonged sodium ion exchange across neuronal membranes, resulting in constant nerve discharge followed by spastic paralysis and death.
When both ingredients are combined, the neurotoxic stimulation is greater than that seen with either ingredient alone.

Style Item Number Model Number UPC
4-10lb 405851 001 724089203649
11-20lb 405851 002 724089203809
21-55lb 405851 003 724089204028
Over 55lb 405851 004 724089204295

Product Reviews by Customers

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Browse 3 questions Browse 3 questions and 27 answers
Why did you choose this?
1800PetSupplies.com Store
Best value
Debra S on Oct 21, 2018
This product works! My lab loves to swim and this product keeps on working regardless of her swimming. Great price!
Mary H on Jan 19, 2018
Best value
Debra S on Oct 21, 2018
like it because it repels and kills fleas, ticks and mosquitoes.
cheryl h on May 30, 2018
This product works! My lab loves to swim and this product keeps on working regardless of her swimming. Great price!
Mary H on Jan 19, 2018
It works!
Barbara F on Jun 9, 2017
Used before with excellent results
Connie S on Mar 3, 2017
We've been using K9 Advantage to control fleas since it first came out with excellent results. We use Advantix if we're going to be in an area that also has ticks - again with excellent results.
Mary A G on Feb 18, 2017
Best defense against fleas, ticks, and mosquitos. Leaves no odor behind. Easy to apply.
Annie S on Sep 11, 2016
Like product, but I must stay on top of flea control from beginning of spring. Especially if dogs are in and out of barn with me daily. Have 3 extra large dogs so gets pricey if you get infestation.
Carol F on Sep 2, 2016
Works the best
Linda R on Jul 26, 2016
our dogs are indoor/outdoor. they love to run the 5 acres.
ROGER B on Apr 13, 2016
It works and I have two dogs so this will last me 6 months
RORI R on Dec 23, 2015
No fleas since I switched to this product. Oklahoma can be bad for fleas just about all year long. Previous product did not work during a particularly tough season. What I thought I was saving by trying other product, I more than made up with the cost and time trying to get rid of the fleas.
Susan R on Nov 29, 2015
Used Frontline plus and just doesn't seem to work as well anymore....plus this product covers more on my pets!
Rebecca G on Aug 24, 2015
very reliable source, also affordable
Laura L on Jun 30, 2015
needed it
eric l on May 23, 2015
used it before and was happy with results
Christi S on Apr 29, 2015
Never see a flea or tick on any of my dogs with this product. Been using it for years with no problems.
Rodney F on Apr 20, 2015
Ive used this med before for my dog and had great results!
heather a on Mar 25, 2015
Product works and I have 2 dogs-like to have product in stock so I don't have to worry
CRYSTAL M on Mar 2, 2015
I have a 1 year supply and only need to purchase at the start of the new year
ALCANTO D on Jan 23, 2015
Was recommended
Carla P on Jan 12, 2015
Provides good flea protection with the added benefit of tick and mosquito protection too.
Mary V on Jan 3, 2015
Dog has fleas & ticks
Aundrea B on Oct 21, 2014
Vet recommended
Lilli O on Jun 16, 2014
Clifford W on Jun 7, 2014
better control of ticks and fleas
Cheryle C on May 12, 2014
like it because it repels and kills fleas, ticks and mosquitoes.
cheryl h on May 30, 2018
It works!
Barbara F on Jun 9, 2017
what is difference between K9 Advantix ll and regular Advantix ll?
Robin N on Sep 7, 2014
Is there a extra 30% at the check out?
A shopper on Apr 1, 2017
BEST ANSWER: no it has expired