Frontline Plus for Dogs - 3 Month Supply

Regularly: $58.69
Today's savings: 36%

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In Stock. Usually Ships within 24 hours.

23-44 Lbs.


In Stock. Usually Ships within 24 hours.

45-88 Lbs.


Temporarily Oversold. Backorder Now! Estimated In Stock by 10/22/2019.

89-132 Lbs


In Stock. Usually Ships within 24 hours.

Shipping weight = 0.08 lb.



Product Summary:

FRONTLINE Plus for Dogs 3-Month Supply

Freeze! FRONTLINE® Plus stops disease-carrying fleas, ticks, and chewing lice in their tracks. It paralyzes the nervous system of these pests, effectively killing them, and prevents the development of flea eggs and larvae. This waterproof formula stays strong even after swimming, bathing, or playing in the rain. One easy, monthly application of FRONTLINE® Plus keeps itching at bay. Available in four sizes; select according to your dog’s weight. Consult your vet before using.


  • Effectively kills fleas, flea eggs, ticks, and chewing lice
  • Reduces the risk of parasite-transmitted infectious disease
  • Fast and easy dermal application
  • Only one application a month necessary
  • Safe for puppies eight weeks or older and dogs of all sizes
  • Approved for breeding, pregnant, and lactating dogs
  • Waterproof
  • 3-month supply
Item Specifications:

3-month supply

For dogs weighing:
5-22 lb.
23-44 lb.
45-88 lb.
89-132 lb.

Active Ingredients:
Fipronil: 9.8%
S-methoprene: 8.8%

Style Item Number Model Number UPC
5-22lbs. 150929 2S P004FLTSP-0-22 891962001064
23-44 Lbs. 150929 3M P004FLTSP-23-44 350604287100
45-88 Lbs. 150929 4L P004FLTSP-45-88 350604287209
89-132 Lbs 150929 5LX P004FLTSP-89-132 350604287308

Product Reviews by Customers

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Browse 9 questions Browse 9 questions and 59 answers
Why did you choose this? Store
have used this for years on my pets
Ronna P on Aug 13, 2019
I've always used it, never fails
Barbara C on Jun 1, 2019
have used this for years on my pets
Ronna P on Aug 13, 2019
Flea control for dog.
Diane U on Jun 12, 2019
I've always used it, never fails
Barbara C on Jun 1, 2019
Because this product works best for my Maggie.
Carol A O on May 20, 2019
Because this works very well and much cheaper than getting it at the vet clinic.<br />I don't like fleas and ticks on my dogs!
Anne F on Apr 5, 2019
I've used this on my dogs since they were born
Cheryl R on Apr 4, 2019
it works well
Patricia S on Mar 27, 2019
works the best
philip b on Feb 8, 2019
Works for little guy.
KEITHYLYNN P on Oct 2, 2018
I tried Advantix II, but my dog was still full of ticks. Went back to Frontline, and no more tick problems.
Michele W on Aug 6, 2018
Has always worked my pets
Barbara C on Jul 3, 2018
It works for my shih zhu and the product is inexpensive.
KEITHYLYNN P on May 16, 2018
prior experience
SAMMIE M on May 12, 2018
Shirley M on Feb 8, 2018
it works
sharon k on Oct 1, 2017
This is a reliable product to keep our dog free from ticks!
Donna E on Sep 2, 2017
we have only ever use this product and have never had any flea issues
Nancy S on Jul 18, 2017
Heard that this was a very good & effective product.
wanda s on Jun 13, 2017
Works great
SuzAnne B on Jun 2, 2017
works great for my dog chester, golden retriever 12 years old
richard k on May 1, 2017
My dog has been chewing the red barn filled bones for years and she loves them.<br />the Rainbow twister and the Ranch Natural rawhide are for gifts.
DIANE D on Sep 30, 2016
It works well for my baby!
Marjorie T on Sep 1, 2016
Its the item I prefer for my canine.
Lori M on Aug 11, 2016
This is the best flea product on the market.
Missy W on Jul 22, 2016
I like frontline plus,because it has always worked for my dogs
Roberta B on Jul 13, 2016
Best price I've found anywhere.
Zachary M on May 22, 2016
This product was recommended by my vet.
Susan L on May 15, 2016
Easy process.
Phillip Y on Apr 18, 2016
They are what we usually purchase from our vet.
Tammy C on Mar 29, 2016
Eve M on Mar 23, 2016
Christmas Gift
Audrey W on Nov 30, 2015
I have used Frontline Plus for a year now and it's great! Our dogs have had no ill effects and they are tick and flea free. Good stuff.
Jackie C on Nov 15, 2015
I wanted to try something; and this seemed to be the only flea item for small dogs.
Judith R on Nov 3, 2015
I have used Frontline forever because this is the only brand that really works to kill the fleas.
Rosemary C on Sep 29, 2015
Have used this for several years and my dogs have no adverse effects. Keeps fleas and ticks off.
Susan S on Aug 31, 2015
it works
Elizabeth D on Aug 6, 2015
proven, tried and true
Leslie A on Aug 1, 2015
Good product and works!
Carole C on Jul 29, 2015
The product is the best for my dog and the price was just right.
Martha D on Jul 24, 2015
Because I have trust Frontline for years
Margaret W on Jul 8, 2015
I bought frontline because it suppose to be the best.
Wendy M on Jun 1, 2015
Easy and reliable product to use...
Brian F on May 19, 2015
So my dog doesn't get fleas
Kyndra R on May 15, 2015
It's summer!
Karen N on May 6, 2015
I've used it before and it seems to work.
Barbara P on May 1, 2015
Works great and no side effects
Kathleen R on Apr 30, 2015
good and trusted product
Penny H on Apr 21, 2015
Recommended as high quality product for flea & tick control
Michelle T on Apr 11, 2015
Good value
Patricia C on Apr 10, 2015
Have used this product easily for my greyhound whose nose is always on the ground.
Nancy L on Apr 9, 2015
Flea control for dog.
Diane U on Jun 12, 2019
Because this product works best for my Maggie.
Carol A O on May 20, 2019
Directions for applying?
A shopper on Apr 11, 2019
BEST ANSWER: Part the hair between their shoulders where you can see the skin, squeeze entire container in that area. Don’t pet that location or give a bath for at least 24 hours.
My dog weight is 10 pda and she won't chew med. Is it ok and will it still work if I have her swallow med?
Balinda A on Apr 10, 2019
BEST ANSWER: This Frontline medication is a topical treatment and can not be given orally.
We have 6 English Mastiffs and the do weight much higher then 135 so would this work on or babies?
Valerie S on May 1, 2018
BEST ANSWER: If the weight of your pet is higher than 132 lbs, you would need more than one pack. You would match the weight of the pet. Item is also required to have a vets approval so this would need prescription.
Expire date on Frontline plus 23-44lbs 3 tubes or 6 tubes?
Judy H on Jan 28, 2018
BEST ANSWER: Due to our constantly rotating stock, we are unable to provide the definite expiration dates that you would receive. We are committed to ensuring our Customers are sent quality, in-date items. If you were to receive an expired product, please contact our Customer Service Team at 1-888-809-0748.
Is this safe for dogs under 4 lbs.? I have 2 Yorkies, both around 3.5 lbs. & most stuff I've seen only lists down to 4 lbs.
Mike S on Jun 11, 2017
BEST ANSWER: Hi there,

I apologize, per the manufacturer's label, this product is recommended for dogs weighing 5 pounds or more.
Is this product safe around my cat who plays with our dog?
Martha V on Apr 25, 2016
BEST ANSWER: You may want to check with a vet or the manufacturer to confirm this question.
Do you have Frontline flea and tick control in chewables for dogs?
Geneva F on Jun 22, 2015
BEST ANSWER: No, we do not currently carry Frontline in a chewable form.
How do I delete an item from my shopping cart?
A shopper on Jun 19, 2015
BEST ANSWER: When you are in your shopping cart , there are 4 options under the quantity box. The 4th option down is "delete" . You would select this option to remove the item .