CLINDAMYCIN HYDROCHLORIDE DROPS
Clindamycin Hydrochloride Liquid
Clindamycin Hydrochloride Drops - for use in dogs and cats is indicated for the treatment of infections caused by susceptible strains of the designated microorganisms in the specific conditions listed below:
Dogs: Skin infections (wounds and abscesses) due to coagulase positive staphylococci (Staphylococcus aureus or Staphylococcus intermedius). Deep wounds and abscesses due to Bacteroides fragilis, Prevotella melaninogenicus, Fusobacterium necrophorum and Clostridium perfringens. Dental infections due to Staphylococcus aureus, Bacteroides fragilis, Prevotella melaninogenicus, Fusobacterium necrophorum and Clostridium perfringens. Osteomyelitis due to Staphylococcus aureus, Bacteroides fragilis, Prevotella melaninogenicus, Fusobacterium necrophorum and Clostridium perfringens.
Cats: Skin infections (wounds and abscesses) due to Staphylococcus aureus, Staphylococcus intermedius and Streptococcus spp. Deep wounds and infections due to Clostridium perfringens and Bacteroides fragilis. Dental infections due to Staphylococcus aureus, Staphylococcus intermedius, Streptococcus spp., Clostridium perfringens and Bacteroides fragilis.
DOSAGE AND ADMINISTRATION
Dogs:
Infected Wounds, Abscesses and Dental Infections
Oral: 2.5 - 15.0 mg/lb body weight every 12 hours.
Duration: Treatment with Clindamycin Hydrochloride Drops products may be continued up to a maximum of 28 days if clinical judgment indicates. Treatment of acute infections should not be continued for more than three or four days if no response to therapy is seen.
Dosage Schedule:
Clindamycin Hydrochloride Drops, administer 1-6 mL/10 lbs body weight every 12 hours.
Dogs:
Osteomyelitis
Oral: 5.0-15.0 mg/lb body weight every 12 hours.
Duration: Treatment with Clindamycin Hydrochloride Drops is recommended for a minimum of 28 days. Treatment should not be continued for longer than 28 days if no response to therapy is seen.
Dosage Schedule:
Clindamycin Hydrochloride Drops, administer 2-6 mL/10 lbs body weight every 12 hours.
Cats:
Infected Wounds, Abscesses and Dental Infections
5.0 - 15.0 mg/lb body weight once every 24 hours depending on the severity of the condition.
Duration: Treatment with Clindamycin Hydrochloride Drops may be continued up to a maximum of 14 days if clinical judgment indicates. Treatment of acute infections should not be continued for more than three to four days if no clinical response to therapy is seen.
Dosage Schedule:
Clindamycin Hydrochloride Drops, to provide 5.0 mg/lb, administer 1 mL/5 lbs body weight once every 24 hours; to provide 15.0 mg/lb, administer 3 mL/5 lbs body weight once every 24 hours.
CONTRAINDICATIONS
Clindamycin Hydrochloride Drops is contraindicated in animals with a history of hypersensitivity to preparations containing clindamycin or lincomycin.
Because of potential adverse gastrointestinal effects, do not administer to rabbits, hamsters, guinea pigs, horses, chinchillas or ruminating animals.
HUMAN WARNINGS
Keep out of reach of children. Not for human use.
PRECAUTIONS
During prolonged therapy of one month or greater, periodic liver and kidney function tests and blood counts should be performed.
The use of Clindamycin Hydrochloride Drops occasionally results in overgrowth of non-susceptible organisms such as clostridia and yeasts. Therefore, the administration of Clindamycin Hydrochloride Drops should be avoided in those species sensitive to the gastrointestinal effects of clindamycin (see CONTRAINDICATIONS). Should superinfections occur, appropriate measures should be taken as indicated by the clinical situation.
Patients with very severe renal disease and/or very severe hepatic disease accompanied by severe metabolic aberrations should be dosed with caution, and serum clindamycin levels monitored during high-dose therapy.
Clindamycin hydrochloride has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents. Therefore, Clindamycin Hydrochloride Drops should be used with caution in animals receiving such agents.
Safety in gestating bitches and queens or breeding male dogs and cats has not been established.
ADVERSE REACTIONS
Side effects occasionally observed in either clinical trials or during clinical use were vomiting and diarrhea.
HOW SUPPLIED
Equivalent to 25 mg per mL clindamycin
Clindamycin Hydrochloride Drops is available as 20 mL filled in 30 mL bottles (25 mg/mL) supplied in packers containing 12 cartoned bottles with direction labels and calibrated dosing droppers.
Store at controlled room temperature between 20° to 25° C (68° to 77° F) [see USP].
Keep container tightly closed when not in use.
FOR ANIMAL USE ONLY
KEEP OUT OF REACH OF CHILDREN