Advantage II for Dogs 6-Month Supply

Regularly: $86.99
Today's savings: 32%

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In Stock. Usually Ships within 24 hours.



In Stock. Usually Ships within 24 hours.



In Stock. Usually Ships within 24 hours.

Over 55lb


In Stock. Usually Ships within 24 hours.

Shipping weight = 0.20 lb.


Product Summary:

Advantage II Dog: 6-Month Supply

This once-a-month topical treatment for fleas and lice on dogs and puppies seven weeks and older features a new formula with insect growth regulatory (IGR) to kill all life stages of fleas and contains Imidacloprid, which acts to disable a flea’s nervous system.


  • Kills all flea life stages, preventing fleas on treated pets from infesting your home
  • Kills adult fleas already on a pet within 12 hours, and re-infesting fleas within two hours
  • Waterproof
  • Fast and easy dermal application
  • Only one application a month necessary
  • Safe for puppies (7 weeks old) and dogs
Item Specifications:

Apply entire contents of tube on the dog's back between the shoulder blades. Apply monthly.

Length of Effectiveness:
Under normal conditions, product is effective for a month. However, in cases of severe flea infestation, retreatment may be necessary earlier than four weeks. Do not retreat more often than once every seven days. After flea control is attained, return to a monthly retreatment schedule.

Active Ingredients:
9.1% Imidacloprid
0.46% Pyripoxyfen
90.44% other ingredients

3-10 lb. – Green
11-20 lb. – Teal
21-55 lb. – Red
Over 55 lb. – Blue
Downloadable Resources
ChartAdvantage II
MSDSAdvantage II
Style Item Number Model Number UPC
3-10lb 405591 001 5420259 724089202598
11-20lb 405591 002 5420275 724089202758
21-55lb 405591 003 5420291 724089202918
Over 55lb 405591 004 5420321 724089203212

Product Reviews by Customers

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Browse 4 questions Browse 4 questions and 45 answers
Why did you choose this? Store
I heard that this was the best brand to use for flea and ticks! We have two dogs so saving money is a must!
Gigi M on Jun 4, 2019
My vet recommended this for my animals.
Donna V on Oct 18, 2018
I heard that this was the best brand to use for flea and ticks! We have two dogs so saving money is a must!
Gigi M on Jun 4, 2019
my preferred method.
Fred G on Feb 25, 2019
My vet recommended this for my animals.
Donna V on Oct 18, 2018
works best of any i've tried
Stephen W on Sep 17, 2018
works good
Deborah D on Aug 29, 2018
tried other brands and they were not as effective as advantage
heather y on Aug 23, 2018
I have been using this product for many, many years and it has always worked on my dogs. The prices on this site are awesome. My dogs also love the peanut butter yogurt chew treats...they look forward to them every day and I have them on auto ship. Thank you for supplying great products at affordable prices!
Lisa S on Jun 5, 2018
Usually use another brand, but this had real good reviews so decided to give it a try, hopefully won't be disappointed.
Shari W on May 18, 2018
shopathome coupons of 30% back and free shipping.
Donna G on May 11, 2018
the lower price
Elizabeth B on Mar 20, 2018
this product always works well
Sue G on Feb 19, 2018
I have tried other brands. They did not work. My Vet recommended Advantage.
Donna V on Feb 2, 2018
This is the only thing that works, even if your dog already has fleas, it will kill them.
Alison T on Oct 12, 2017
Used it before and has been excellent for flea control. Discount was great too!
ofir s on Aug 12, 2017
good product
Susan G on Jun 22, 2017
Because it was highly recommended by my vet.
Alma L on Jun 9, 2017
My vet recommended this item. He said that Frontline does not work as good as Advantage.
Donna V on May 15, 2017
Kirk N on Apr 23, 2017
Been using it for years. It works.
daniel p on Apr 14, 2017
best price
Wendy B on Feb 16, 2017
because it really works.
pete w on Feb 8, 2017
works great
Jon R on Dec 22, 2016
I use this item on my animals, this was a very good price.
Kathy W on Jul 19, 2016
need and price
Jane W on Jul 10, 2016
Pam M on Mar 2, 2016
I've used this product in the past and my pet has never had a problem with fleas.
Sandy R on Oct 21, 2015
Excellent product
KEVIN K on Oct 2, 2015
seem to be the best product for my dog
LANI K on Jul 26, 2015
My dogs needed flea & tick control, & I read good reviews about Advantage II.
Marie K on Jul 2, 2015
Patricia C on Apr 14, 2015
vet reccomendation
eva n on Apr 14, 2015
great price
Lnda C on Dec 20, 2014
Needed flea tx
maurine b on Dec 6, 2014
Advantage really works better than frontline. Stays on pets longer.
Deborah C on Nov 19, 2014
I have purchased this before and it is the best defense, easy to apply and gives my pet necessary protection.
Shelly H on Sep 15, 2014
because it works
Armand H on Aug 24, 2014
I've tried other brands in the past, but this one has always worked better for me.
jeff c on Mar 31, 2014
Good deal
Amy S on Mar 28, 2014
my preferred method.
Fred G on Feb 25, 2019
works best of any i've tried
Stephen W on Sep 17, 2018
This price is for a 6 month supply, meaning 6 doses? The page is a bit ambiguous on the quantity.
d p on Apr 7, 2017
BEST ANSWER: The 6 month supply is for 1 dose per month for 6 months.
Is this for 10 lb dog?
Mary E on Jun 23, 2015
BEST ANSWER: I have been giving my 10 lb. dog the Advantage II for about 2 years and have found it very effective with no side effects.
Does this work on ticks?
A shopper on Mar 22, 2015
BEST ANSWER: The item only refers to having protection again fleas.